Avermectin induces the oxidative stress, genotoxicity, and immunological responses in the Chinese Mitten Crab, Eriocheir sinensis

Yi Huang, Yuhang Hong, Zhiqiu Huang, Jilei Zhang and Qiang Huang

PLOS ONE, 2019, vol. 14, issue 11, 1-16

Abstract: Avermectin is commonly used in aquaculture systems for pest control in recent decades in China. However, no information is provided for the toxic effect to the important commercial species, Chinese mitten crab, Eriocheir sinensis. To investigate the aquatic toxicity of avermectin, an acute toxic test was performed in this study. The results showed that the 48 h- and 96 h- LC50 were 1.663 and 0.954 mg/L, respectively. For further research, crabs were exposed to sublethal concentrations of 0.03, 0.06, 0.12, 0.24 and 0.48 mg/L. Levels of antioxidants, including superoxide dismutase (SOD), catalase (CAT) and total antioxidant capacity (T-AOC) were significantly (P

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0225171

DOI: 10.1371/journal.pone.0225171

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