Clinical impact of visceral-to-subcutaneous fat ratio in patients with acute aortic dissection

Yusuke Miura, Satoshi Higuchi, Kenichi Matsushita, Toshiya Kariyasu, Haruhiko Machida, Kenichi Yokoyama, Kyoko Soejima and Toru Satoh

PLOS ONE, 2019, vol. 14, issue 12, 1-13

Abstract: Background: Obesity has increased worldwide. Although the visceral-to-subcutaneous fat ratio (VS ratio) is an established risk factor for cardiovascular disease, its clinical impact on the long-term prognosis of patients with acute aortic dissection (AAD) remains unclear. Materials and methods: This retrospective study included 111 patients with AAD admitted to our hospital from 2013 to 2016. Patients who died during hospitalization, and those diagnosed with Marfan’s syndrome were excluded. Visceral and subcutaneous fat accumulation (VFA, SFA) at umbilical level were calculated on a dedicated workstation. Major Adverse Cardiovascular and Cerebrovascular Events (MACCE) and worsening renal function (WRF) at 3 years were evaluated. Results: Patient characteristics were as below: age, 73 ± 13; male, 55%; Stanford type A, 53%. Average VFA, SFA, and VS ratio on admission were 98 (52–145) cm2, 141 (90–185) cm2, and 0.75 (0.47–0.97), respectively. VFA was higher in male than in female (male, 134 [84–179] cm2; female, 71 [46–99] cm2; p

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0226642

DOI: 10.1371/journal.pone.0226642

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