Quantitative evaluation of choriocapillaris using optical coherence tomography and optical coherence tomography angiography in patients with central serous chorioretinopathy after half-dose photodynamic therapy

Hyun Seung Yang, Tae Gu Kang, Hyun Park, Ji Su Heo, Jonghoon Park, Kyung Sub Lee and Sangkyung Choi

PLOS ONE, 2020, vol. 15, issue 1, 1-14

Abstract: Purpose: To quantify the structural and perfusion changes in choriocapillaris in chronic central serous chorioretinopathy after half-dose photodynamic therapy by using spectral-domain optical coherence tomography and optical coherence tomography angiography. Methods: This retrospective interventional case series examined the eyes of patients with central serous chorioretinopathy. Patients underwent full ophthalmic examinations, including spectral-domain optical coherence tomography and angiography, prior to and 1, 3, and 6 months after the treatment. Clinical and tomographic features of the choriocapillaris and choroidal thickness and vascular changes were evaluated by assessing flow signal voids. Results: All 56 eyes of 56 patients showed complete resolution of subretinal fluid at 3 months after photodynamic therapy. The best-corrected visual acuity significantly improved at 6 months (p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0227718

DOI: 10.1371/journal.pone.0227718

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