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Predictive factors of first dosage intravenous immunoglobulin-related adverse effects in children

Jun Kubota, Shin-ichiro Hamano, Atsuro Daida, Erika Hiwatari, Satoru Ikemoto, Yuko Hirata, Ryuki Matsuura and Daishi Hirano

PLOS ONE, 2020, vol. 15, issue 1, 1-12

Abstract: Background: Intravenous immunoglobulin (IVIG) therapy is used in the treatment of various diseases, and IVIG-related adverse effects (IVIG-AEs) vary from mild to severe. However, the mechanisms underlying IVIG-AEs and the potential predictive factors are not clear. This study investigated whether certain IVIG-AEs can be predicted before IVIG administration. Study design and methods: This retrospective cohort study at the Division of Neurology, Saitama Children’s Medical Center included patients enrolled from 2008 to 2018 who were

Date: 2020
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DOI: 10.1371/journal.pone.0227796

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