Association of early viral lower respiratory infections and subsequent development of atopy, a systematic review and meta-analysis of cohort studies

Sebastien Kenmoe, Cyprien Kengne-Nde, Abdou Fatawou Modiyinji, Jean Joel Bigna and Richard Njouom

PLOS ONE, 2020, vol. 15, issue 4, 1-15

Abstract: Introduction: Existing evidence on the relationship between childhood lower respiratory tract infections (LRTI) and the subsequent atopy development is controversial. We aimed to investigate an association between viral LRTI at 2 years. Methods: We conducted a search at Embase, Pubmed, Web of Science, and Global Index Medicus. We collected data from the included articles. We estimated the odds ratio and the 95% confidence intervals with a random effect model. We determined factors associated with atopy development after childhood LRTI using univariate and multivariate meta-regression analyses. We recorded this systematic review at PROSPERO with the number CRD42018116955. Results: We included 24 studies. There was no relationship between viral LRTI at

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0231816

DOI: 10.1371/journal.pone.0231816

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