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Treatment effect of posterior scleral reinforcement on controlling myopia progression: A systematic review and meta-analysis

Chih-An Chen, Pao-Yen Lin and Pei-Chang Wu

PLOS ONE, 2020, vol. 15, issue 5, 1-13

Abstract: Background: High myopia is a sight-threatening disease that causes axial length elongation and severe complications. Data on the benefits of posterior scleral reinforcement surgery in myopia control have been conflicting. The purpose of this study was to explore the treatment effect and complications of posterior scleral reinforcement in the treatment of myopia. Methods: Articles were retrieved for relevant studies from inception to July 24, 2019, by PubMed, EMBASE, and Ovid. Analyses were conducted to compare the treatment effects of controlling spherical equivalent refraction and axial length elongation. The weighted mean difference and Hedges’ adjusted g were used to evaluate the treatment effects, with a random-effects model. Heterogeneity was quantified using I2 statistic and explored by subgroup analysis. Publication bias was addressed by funnel plots and Egger’s test. Results: A total of 11 articles were included in this meta-analysis. On estimating the treatment effect, the mean differences of myopia progression and axial length changes between surgery and control groups were 0.41 diopters per year (95% CI 0.21 to 0.61; P

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0233564

DOI: 10.1371/journal.pone.0233564

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