Sex-related impairment and patient needs/benefits in anogenital psoriasis: Difficult-to-communicate topics and their impact on patient-centred care

Neuza da Silva, Matthias Augustin, Anna Langenbruch, Ulrich Mrowietz, Kristian Reich, Diamant Thaçi, Wolf-Henning Boehncke, Natalia Kirsten, Alexandra Danckworth and Rachel Sommer

PLOS ONE, 2020, vol. 15, issue 7, 1-13

Abstract: Genital psoriasis affects 2–5% of psoriasis patients; generalised plaque or intertriginous psoriasis also affects the genital area in 29–40% of cases. Anogenital psoriasis has been associated with significant quality of life impairments, but little is known about specific patient needs/treatment goals. This study aimed to examine the overall and sex-related disease burden, patient needs and treatment benefits in patients with anogenital psoriasis, compared to patients with psoriasis not affecting the anal/genital areas. Within the cross-sectional nationwide survey, 2,009 participants were consecutively recruited in 157 randomly assigned German dermatology practices and clinics, according to the following inclusion criteria aged 18 years or over; diagnosis of psoriasis vulgaris; ability to answer the questionnaires; and written informed consent. Based on a high-resolution grid on the topical distribution of psoriasis, two groups were formed: anogenital psoriasis (n = 622) and comparison group (n = 1,303). Clinical severity was assessed by the Psoriasis Area and Severity Index (PASI). Patients completed the EuroQoL visual analogue scale (EQ VAS), the Dermatology Life Quality Index (DLQI), and the Patient Benefit Index (PBI). Patients with anogenital psoriasis had higher PASI (13.0±10.6 vs. 8.9±7.6, P

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0235091

DOI: 10.1371/journal.pone.0235091

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