Long-term effects on growth of an energy-enhanced parenteral nutrition in preterm newborn: A quasi-experimental study

Gianluca Terrin, Alessandra Coscia, Giovanni Boscarino, Francesca Faccioli, Maria Di Chiara, Carla Greco, Elisa Onestà, Salvatore Oliva, Marina Aloi, Lucia Dito, Viviana Cardilli, Daniela Regoli and Mario De Curtis

PLOS ONE, 2020, vol. 15, issue 7, 1-15

Abstract: Aim: To assess the best energy intake in Parenteral Nutrition (PN) for preterm newborns, considering both possible benefits for growth and risk of complications. Methods: Quasi-experimental study comparing two cohorts of newborns, receiving Energy-Enhanced vs. Standard PN (Cohort A, from 1st January 2015 to 31 January 2016 and Cohort B from 1st February 2016 to 31 March 2017; respectively) after implementation of a change in the PN protocol. The primary outcome measure was growth at 24 months of life. The PN associated complications were also measured. Results: We enrolled 132 newborns in two Cohorts, similar for prenatal and postnatal clinical characteristics. Although, body weight and length at 24 months of life were significantly higher (p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0235540

DOI: 10.1371/journal.pone.0235540

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