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Efficacy of copper-impregnated hospital linen in reducing healthcare-associated infections: A systematic review and meta-analysis

Tingting Fan, Li Shao, Xingzhen Wang and Ping Ren

PLOS ONE, 2020, vol. 15, issue 7, 1-14

Abstract: Background: Healthcare-associated infections (HAI) are a significant burden on the healthcare system. Recent research has suggested the role of copper in reducing HAI. The purpose of this study was to systematically search literature and pool data from studies evaluating the efficacy of copper-impregnated hospital linen in reducing HAI. Methods: We carried out a systematic electronic search of PubMed, ScienceDirect, BioMed Central, Springer, Embase, and Google Scholar databases for controlled studies evaluating the efficacy of copper-impregnated linen in reducing the incidence of HAI. The last search was carried out on 15th February 2020. Results: Six studies were included. There was no restriction on the type of organism causing HAI in three studies while three trials reported HAI from Clostridioides difficile and multi-drug resistant organisms (MDRO). A meta-analysis of six studies indicated the use of copper-impregnated linen did not reduce the risk of HAI [Incidence rate ratio (IRR):0.66, 95% CI:0.28–1.58, p = 0.36, I2 = 100%)]. On subgroup analysis, while pooled data from three studies HAI indicated a statistical significant reduction in all-HAI with copper-impregnated linen (IRR:0.76, 95% CI:0.75–0.77, p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0236184

DOI: 10.1371/journal.pone.0236184

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