Simplifying the screening of gestational diabetes by maternal age plus fasting plasma glucose at first prenatal visit: A prospective cohort study

Yi-Yun Tai, Chien-Nan Lee, Chun-Heng Kuo, Ming-Wei Lin, Kuan-Yu Chen, Shin-Yu Lin and Hung-Yuan Li

PLOS ONE, 2020, vol. 15, issue 8, 1-12

Abstract: Aim: The addition of maternal age to fasting plasma glucose (FPG) at 24–28 gestational weeks improves the performance of GDM screening as maternal age increases. However, this method delays the diagnosis of GDM. Since FPG at the first prenatal visit (FPV) is a screening option for pre-existing diabetes, we evaluated the performance of age plus FPG at the FPV to reduce the need for the OGTT. Methods: Pregnant women were recruited consecutively in 2013–2018 (the training cohort) and 2019 (the validation cohort). We excluded women with twin pregnancies, unavailable FPG at the FPV or OGTT data, pre-pregnancy diabetes, or a history of GDM. All participants underwent FPG and haemoglobin A1c (HbA1c) at the FPV and received 75-g OGTT at 24–28 gestational weeks if FPG at the FPV was

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0237224

DOI: 10.1371/journal.pone.0237224

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