Improved glycaemic variability and basal insulin dose reduction during a running competition in recreationally active adults with type 1 diabetes—A single-centre, prospective, controlled observational study

Othmar Moser, Alexander Mueller, Max L Eckstein, Haris Ziko, Felix Aberer, Gerlies Treiber, Christina Unteregger, Harald Kojzar, Julia K Mader, Caren Sourij, Peter Pferschy, Anna Obermayer, Norbert Tripolt and Harald Sourij

PLOS ONE, 2020, vol. 15, issue 9, 1-12

Abstract: Introduction: To investigate the glycaemic response, macronutrient intake and insulin management in people with type 1 diabetes (T1D) compared to healthy individuals around a running competition. Material and methods: This was a single-centre, prospective, controlled observational study performed in individuals with T1D and healthy people. 24 people (12 T1D) were included in this study (age: T1D 41±12 vs. healthy 38±6 years, females: 3 vs. 6, BMI: 25.53.0 vs. 22.9±2.8 kg/m2). Both groups received an intermittently scanned continuous glucose monitoring (isCGM; FreeStyle Libre 1, Abbott, USA) system to assess glycaemia 24 hours before, during and 24 hours after a running competition. During this period, participants recorded their food intake and insulin administration. Data were analysed via ANOVA and mixed model analyses with post-hoc testing (p≤0.05). Results: For overall glycaemic ranges in comparison of groups, significant differences were found for time in range (T1D 63±21% vs. healthy 89±13%, p = 0.001), time above range (TAR) 1 (T1D 21±15% vs. healthy 0±0%, p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0239091

DOI: 10.1371/journal.pone.0239091

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