Physiological changes in retinal layers thicknesses measured with swept source optical coherence tomography

Elisa Viladés, Amaya Pérez-del Palomar, José Cegoñino, Javier Obis, María Satue, Elvira Orduna, Luis E Pablo, Marta Ciprés and Elena Garcia-Martin

PLOS ONE, 2020, vol. 15, issue 10, 1-14

Abstract: Purpose: To evaluate the physiological changes related with age of all retinal layers thickness measurements in macular and peripapillary areas in healthy eyes. Methods: Wide protocol scan (with a field of view of 12x9 cm) from Triton SS-OCT instrument (Topcon Corporation, Japan) was performed 463 heathy eyes from 463 healthy controls. This protocol allows to measure the thickness of the following layers: Retina, Retinal nerve fiber layer (RNFL), Ganglion cell layer (GCL +), GCL++ and choroid. In those layers, mean thickness was compared in four groups of ages: Group 1 (71 healthy subjects aged between 20 and 34 years); Group 2 (65 individuals aged 35–49 years), Group 3 (230 healthy controls aged 50–64 years) and Group 4 (97 healthy subjects aged 65–79 years). Results: The most significant thinning of all retinal layers occurs particularly in the transition from group 2 to group 3, especially in temporal superior quadrant at RNFL, GCL++ and retinal layers (p≤0.001), and temporal superior, temporal inferior, and temporal half in choroid layer (p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0240441

DOI: 10.1371/journal.pone.0240441

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