Remote testing of vitamin D levels across the UK MS population—A case control study

Nicola Vickaryous, Mark Jitlal, Benjamin Meir Jacobs, Rod Middleton, Siddharthan Chandran, Niall John James MacDougall, Gavin Giovannoni and Ruth Dobson

PLOS ONE, 2020, vol. 15, issue 12, 1-13

Abstract: Objective: The association between vitamin D deficiency and multiple sclerosis (MS) is well described. We set out to use remote sampling to ascertain vitamin D status and vitamin D supplementation in a cross-sectional study of people with MS across the UK. Methods: People with MS and matched controls were recruited from across the UK. 1768 people with MS enrolled in the study; remote sampling kits were distributed to a subgroup. Dried blood spots (DBS) were used to assess serum 25(OH)D in people with MS and controls. Results: 1768 MS participants completed the questionnaire; 388 MS participants and 309 controls provided biological samples. Serum 25(OH)D was higher in MS than controls (median 71nmol/L vs 49nmol/L). A higher proportion of MS participants than controls supplemented (72% vs 26%, p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0241459

DOI: 10.1371/journal.pone.0241459

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