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COVID-19 gender susceptibility and outcomes: A systematic review

Ines Lakbar, David Luque-Paz, Jean-Louis Mege, Sharon Einav and Marc Leone

PLOS ONE, 2020, vol. 15, issue 11, 1-15

Abstract: Background: Epidemiological differences between men and women have been reported with regards to sepsis, influenza and severe coronavirus infections including SARS-CoV and MERS-CoV. Aim: To systematically review the literature relating to men versus women on SARS-CoV-2 in order to seek differences in disease characteristics (e.g. infectivity, severity) and outcomes (e.g. mortality). Methods: We searched 3 electronic databases up or observational studies reporting differences between men and women in the SARS-CoV-2 disease characteristics stated. We identified and included 47 studies, reporting data for 21,454 patients mainly from China. Results: The unadjusted mortality rates of men were higher than those of women, with a mortality OR 0.51 [0.42, 0.61] (p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0241827

DOI: 10.1371/journal.pone.0241827

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