A cohort study of 676 patients indicates D-dimer is a critical risk factor for the mortality of COVID-19

Yongsheng Huang, Xiaoyu Lyu, Dan Li, Lin Wang, Yujun Wang, Wenbin Zou, Yingxin Wei and Xiaowei Wu

PLOS ONE, 2020, vol. 15, issue 11, 1-11

Abstract: Coronavirus Disease 2019 (COVID-19) has recently become a public emergency and a worldwide pandemic. However, the information on the risk factors associated with the mortality of COVID-19 and of their prognostic potential is limited. In this retrospective study, the clinical characteristics, treatment and outcome data were collected and analyzed from 676 COVID-19 patients stratified into 140 non-survivors and 536 survivors. We found that the levels of Dimerized plasmin fragment D (D-dimer), C-reactive protein (CRP), lactate dehydrogenase (LDH), procalcitonin (PCT) were significantly higher in non-survivals on admission (non-survivors vs. survivors: D-Dimer ≥ 0.5 mg/L, 83.2% vs. 44.9%, P

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0242045

DOI: 10.1371/journal.pone.0242045

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