Prediction of anterior chamber volume after implantation of posterior chamber phakic intraocular lens

Yuki Takagi, Takashi Kojima, Tomoya Nishida, Tomoaki Nakamura and Kazuo Ichikawa

PLOS ONE, 2020, vol. 15, issue 11, 1-11

Abstract: Purpose: To predict the anterior chamber volume (ACV) after implantable collamer lens (ICL) implantation based on ICL size and parameters of anterior segment optical coherence tomography (AS-OCT). Design: Retrospective study. Methods: This study included 222 eyes of 222 patients who underwent ICL implantation at Nagoya Eye Clinic. The patients were divided into two groups: prediction group, for creating the prediction equation (148 eyes, mean age: 32.11 ± 8.04 years), and verification group, for verifying the equation (74 eyes, mean age: 33.03 ± 6.74 years). The angle opening distance (AOD), anterior chamber width (ACW), ACV, anterior chamber depth, lens vault, angle-to-angle distance, angle recess area, and trabecular iris space area were calculated using AS-OCT. A stepwise multiple regression analysis was performed. After the creation of the prediction equation, its accuracy was verified in the verification group. Results: The ACV, AOD750, ACW, and ICL size were selected as explanatory variables to predict postoperative ACV. Mean predicted (114.2 ± 21.83 mm3) and actual postoperative ACVs (116.1 ± 25.41 mm3) were not significantly different (P = 0.269); absolute error was 10.59 ± 9.13 mm3. In addition, there was high correlation between actual and predictive ACV (adjusted R2 = 0.6996, p

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0242434

DOI: 10.1371/journal.pone.0242434

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