The association of body mass index with functional dyspepsia is independent of psychological morbidity: A cross-sectional study

Keng Hau Beh, Kee Huat Chuah, Nurul Azmi Mahamad Rappek and Sanjiv Mahadeva

PLOS ONE, 2021, vol. 16, issue 1, 1-13

Abstract: Background and aim: The association between body mass index (BMI) and functional gastrointestinal disorders (FGIDs) has been inconsistent. We aimed to explore the association of BMI with FGIDs in a primary care setting to provide more data in this area. Methods: A cross-sectional study of consecutive Asian adults attending a primary healthcare setting was conducted. This study was conducted in 2 phases: The association between BMI and common FGIDs (functional diarrhea/FD, irritable bowel syndrome/IBS, functional diarrhea and functional constipation/FC) was studied initially. The influence of anxiety and depression on BMI and FGIDs was additionally explored in phase 2. Results: A total of 1002 subjects (median age 32 years, 65.4% females, 90.7% Malay ethnicity, 73.2% higher than secondary level education) were recruited between August 2019 to January 2020. The majority of subjects were obese (39.2%), and had central obesity (51.7%), while 6.1% had metabolic syndrome. The prevalence of FD, IBS, functional diarrhea and FC were 7.5% (n = 75), 4.0% (n = 40), 1.2% (n = 12) and 10.5% (n = 105) respectively, based on the Rome III criteria. Among individual FGIDs, FD subjects had more underweight adults (BMI

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0245511

DOI: 10.1371/journal.pone.0245511

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