A systematic review and activation likelihood estimation meta-analysis of the central innervation of the lower urinary tract: Pelvic floor motor control and micturition

Ilse M Groenendijk, Ulrich Mehnert, Jan Groen, Becky D Clarkson, Jeroen R Scheepe and Bertil F M Blok

PLOS ONE, 2021, vol. 16, issue 2, 1-23

Abstract: Purpose: Functional neuroimaging is a powerful and versatile tool to investigate central lower urinary tract (LUT) control. Despite the increasing body of literature there is a lack of comprehensive overviews on LUT control. Thus, we aimed to execute a coordinate based meta-analysis of all PET and fMRI evidence on descending central LUT control, i.e. pelvic floor muscle contraction (PFMC) and micturition. Materials and methods: A systematic literature search of all relevant libraries was performed in August 2020. Coordinates of activity were extracted from eligible studies to perform an activation likelihood estimation (ALE) using a threshold of uncorrected p

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0246042

DOI: 10.1371/journal.pone.0246042

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