The differential impact of pediatric COVID-19 between high-income countries and low- and middle-income countries: A systematic review of fatality and ICU admission in children worldwide

Taito Kitano, Mao Kitano, Carsten Krueger, Hassan Jamal, Hatem Al Rawahi, Rachelle Lee-Krueger, Rose Doulin Sun, Sandra Isabel, Marta Taida García-Ascaso, Hiromi Hibino, Bettina Camara, Marc Isabel, Leanna Cho, Helen E Groves, Pierre-Philippe Piché-Renaud, Michael Kossov, Ikuho Kou, Ilsu Jon, Ana C Blanchard, Nao Matsuda, Quenby Mahood, Anupma Wadhwa, Ari Bitnun and Shaun K Morris

PLOS ONE, 2021, vol. 16, issue 1, 1-12

Abstract: Background: The overall global impact of COVID-19 in children and regional variability in pediatric outcomes are presently unknown. Methods: To evaluate the magnitude of global COVID-19 death and intensive care unit (ICU) admission in children aged 0–19 years, a systematic review was conducted for articles and national reports as of December 7, 2020. This systematic review is registered with PROSPERO (registration number: CRD42020179696). Results: We reviewed 16,027 articles as well as 225 national reports from 216 countries. Among the 3,788 global pediatric COVID-19 deaths, 3,394 (91.5%) deaths were reported from low- and middle-income countries (LMIC), while 83.5% of pediatric population from all included countries were from LMIC. The pediatric deaths/1,000,000 children and case fatality rate (CFR) were significantly higher in LMIC than in high-income countries (HIC) (2.77 in LMIC vs 1.32 in HIC; p

Date: 2021
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0246326 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 46326&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0246326

DOI: 10.1371/journal.pone.0246326

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().