Biochemical recurrence after radical prostatectomy according to nadir prostate specific antigen value

Jae Hoon Chung, Jae Yong Jeong, Ji Youl Lee, Was Song, Minyong Kang, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong IL Seo, Hyun Moo Lee and Seong Soo Jeon

PLOS ONE, 2021, vol. 16, issue 5, 1-10

Abstract: The hypersensitive prostate specific antigen (PSA) test can measure in 0.01 ng/mL units, and its efficacy for screening after radical prostatectomy (RP) has been reported. In this study, we assessed patients who underwent RP to evaluate whether the nadir value affects biochemical recurrence (BCR). From 1995 to 2014, patients classified as N0 who had negative resection margins and a nadir PSA of less than 0.2 ng/mL were evaluated. The characteristics, pathological outcomes, PSA after RP, and BCR were assessed. A total of 1483 patients were enrolled. Among them, 323 (21.78%) patients showed BCR after RP. The mean age of the BCR group was 63.86±7.31 years, and while that of the no-recurrence group was 64.06±6.82 years (P = 0.645). The mean preoperative PSA of the BCR group was 9.75±6.92 ng/mL and that of the no-recurrence group was 6.71±5.19 ng/mL (P

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0249709

DOI: 10.1371/journal.pone.0249709

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