Racial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project

Jason H Karnes, Amit Arora, Jianglin Feng, Heidi E Steiner, Lina Sulieman, Eric Boerwinkle, Cheryl Clark, Mine Cicek, Elizabeth Cohn, Kelly Gebo, Roxana Loperena-Cortes, Lucila Ohno-Machado, Kelsey Mayo, Steve Mockrin, Andrea Ramirez, Sheri Schully and Yann C Klimentidis

PLOS ONE, 2021, vol. 16, issue 8, 1-13

Abstract: Differences in obesity and body fat distribution across gender and race/ethnicity have been extensively described. We sought to replicate these differences and evaluate newly emerging data from the All of Us Research Program (AoU). We compared body mass index (BMI), waist circumference, and waist-to-hip ratio from the baseline physical examination, and alanine aminotransferase (ALT) from the electronic health record in up to 88,195 Non-Hispanic White (NHW), 40,770 Non-Hispanic Black (NHB), 35,640 Hispanic, and 5,648 Asian participants. We compared AoU sociodemographic variable distribution to National Health and Nutrition Examination Survey (NHANES) data and applied the pseudo-weighting method for adjusting selection biases of AoU recruitment. Our findings replicate previous observations with respect to gender differences in BMI. In particular, we replicate the large gender disparity in obesity rates among NHB participants, in which obesity and mean BMI are much higher in NHB women than NHB men (33.34 kg/m2 versus 28.40 kg/m2 respectively; p

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0255583

DOI: 10.1371/journal.pone.0255583

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