Association between hepatic oxygenation on near-infrared spectroscopy and clinical factors in patients undergoing hemodialysis

Yuichiro Ueda, Susumu Ookawara, Kiyonori Ito, Yusuke Sasabuchi, Hideyuki Hayasaka, Masaya Kofuji, Takayuki Uchida, Sojiro Imai, Satoshi Kiryu, Saori Minato, Haruhisa Miyazawa, Hidenori Sanayama, Keiji Hirai, Kaoru Tabei and Yoshiyuki Morishita

PLOS ONE, 2021, vol. 16, issue 10, 1-12

Abstract: The hepato-splanchnic circulation directly influences oxygenation of the abdominal organs and plays an important role in compensating for the blood volume reduction that occurs in the central circulation during hemodialysis (HD) with ultrafiltration. However, the hepato-splanchnic circulation and oxygenation cannot be easily evaluated in the clinical setting of HD therapy. We included 185 HD patients and 15 healthy volunteers as the control group in this study. Before HD, hepatic regional oxygen saturation (rSO2), a marker of hepatic oxygenation reflecting the hepato-splanchnic circulation and oxygenation, was monitored using an INVOS 5100c oxygen saturation monitor. Hepatic rSO2 was significantly lower in patients undergoing HD than in healthy controls (56.4 ± 14.9% vs. 76.2 ± 9.6%, p

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0259064

DOI: 10.1371/journal.pone.0259064

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