Long-term characteristics of exudative age-related macular degeneration in Japanese patients

Masaaki Saito, Tomohiro Iida, Kuniharu Saito, Mariko Kano, Kanako Itagaki, Ichiro Maruko and Tetsuju Sekiryu

PLOS ONE, 2021, vol. 16, issue 12, 1-15

Abstract: Purpose: The present study aimed to evaluate the clinical characteristics of exudative age-related macular degeneration (AMD) in Japanese patients over a 10-year period and to compare the past our report. Methods: We retrospectively reviewed 1,600 treatment-naïve patients (1,777 eyes) with exudative AMD. The 10 years were divided into 2-year phases I to V. Results: Of the 1,600 patients, 720 (45.0%), 733 (45.8%), 98 (6.1%), and 49 (3.1%) were diagnosed with typical AMD, polypoidal choroidal vasculopathy (PCV), retinal angiomatous proliferation, and combined subtypes, respectively. The prevalence of PCV decreased from 54.7% in phase I to 46.0% at phase V. Of the 1,777 eyes, the mean baseline logarithm of the minimum angle of resolution best-corrected visual acuities (BCVAs) in phases I, II, III, IV, and V were 0.70, 0.66, 0.55, 0.50, and 0.48, respectively. Phases III, IV, and V had significantly (P = 0.0012, P

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0261320

DOI: 10.1371/journal.pone.0261320

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