Cost-effectiveness of the TherMax blood warmer during continuous renal replacement therapy

Michael J Blackowicz, Max Bell, Jorge Echeverri, Kai Harenski and Marcus E Broman

PLOS ONE, 2022, vol. 17, issue 2, 1-10

Abstract: Hypothermia is a common adverse event during continuous renal replacement therapy (CRRT), affecting multiple organ systems and increasing risk of poor health outcomes among patients with acute kidney injury (AKI) undergoing CRRT. TheraMax blood warmers are the next generation of extracorporeal blood warmers which reduce risk of hypothermia during CRRT. The purpose of this study is to elucidate the potential health economic impacts of avoiding CRRT-induced hypothermia by using the novel TherMax blood warming device. This study compares health care costs associated with use of the new TherMax blood warmer unit integrated with the PrisMax system compared to CRRT with a standalone blood warming device to avoid hypothermia in continuous renal replacement therapy (CRRT). An economic model was developed in which relevant health states for each intervention were normothermia, hypothermia, discharge, and death. Clinical inputs and costs were obtained from a combination of retrospective chart review and publicly available summary estimates. The proportion of AKI patients treated with CRRT who became hypothermic (

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0263054

DOI: 10.1371/journal.pone.0263054

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