Predictors of life-threatening complications in relatively lower-risk patients hospitalized with COVID-19

Christopher J Gonzalez, Cameron J Hogan, Mangala Rajan, Martin T Wells, Monika M Safford, Laura C Pinheiro, Arnab K Ghosh, Justin J Choi, Clare A Burchenal, Pooja D Shah and Martin F Shapiro

PLOS ONE, 2022, vol. 17, issue 2, 1-13

Abstract: Older individuals with chronic health conditions are at highest risk of adverse clinical outcomes from COVID-19, but there is widespread belief that risk to younger, relatively lower-risk individuals is negligible. We assessed the rate and predictors of life-threatening complications among relatively lower-risk adults hospitalized with COVID-19. Of 3766 adults hospitalized with COVID-19 to three hospitals in New York City from March to May 2020, 963 were relatively lower-risk based on absence of preexisting health conditions. Multivariable logistic regression models examined in-hospital development of life-threatening complications (major medical events, intubation, or death). Covariates included age, sex, race/ethnicity, hypertension, weight, insurance type, and area-level sociodemographic factors (poverty, crowdedness, and limited English proficiency). In individuals ≥55 years old (n = 522), 33.3% experienced a life-threatening complication, 17.4% were intubated, and 22.6% died. Among those

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0263995

DOI: 10.1371/journal.pone.0263995

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