Cost-effectiveness of a medication event monitoring system for tuberculosis management in Morocco

Jangmi Yang, Hae-Young Kim, Seup Park, Ilham Sentissi, Nathan Green, Byung Kwon Oh, Yujin Kim, Kyung Hyun Oh, Eunseong Paek, Young Joon Park, In-Hwan Oh and Seung Heon Lee

PLOS ONE, 2022, vol. 17, issue 4, 1-12

Abstract: Background: Digital health technologies have been used to enhance adherence to TB medication, but the cost-effectiveness remains unclear. Methods: We used the real data from the study conducted from April 2014 to December 2020 in Morocco using a smart pillbox with a web-based medication monitoring system, called Medication Event Monitoring Systems (MEMS). Cost-effectiveness was evaluated using a decision analysis model including Markov model for Multi-drug resistant (MDR) TB from the health system perspective. The primary outcome was the incremental cost-effectiveness ratio (ICER) per disability adjusted life-year (DALY) averted. Two-way sensitive analysis was done for the treatment success rate between MEMS and standard of care. Results: The average total per-patient health system costs for treating a new TB patient under MEMS versus standard of care were $398.70 and $155.70, respectively. The MEMS strategy would reduce the number of drug-susceptible TB cases by 0.17 and MDR-TB cases by 0.01 per patient over five years. The ICER of MEMS was $434/DALY averted relative to standard of care, and was most susceptible to the TB treatment success rate of both strategies followed by the managing cost of MEMS. Conclusion: MEMS is considered cost-effective for managing infectious active TB in Morocco.

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0267292

DOI: 10.1371/journal.pone.0267292

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