Correlation between relative afferent pupillary defect and visual field defects on Humphrey automated perimetry: A cross-sectional clinical trial

Juthamat Witthayaweerasak, Pemika Lertjittham and Nipat Aui-aree

PLOS ONE, 2022, vol. 17, issue 5, 1-11

Abstract: Purpose: To evaluate the correlations between relative afferent pupillary defect (RAPD) magnitude, assessed using the clinical plus scale and neutral density filters, and visual field parameters in patients with unilateral or asymmetrical bilateral optic neuropathy or retinopathy. Methods: Fifty-two patients with RAPD, graded by the swinging flashlight test and neutral density filters, were analyzed in this cross-sectional trial. The RAPD clinical plus scale was divided into grade 1+, initial weak constriction; grade 2+, initial stall then dilatation; grade 3+, immediate dilatation; and grade 4+, fixed amaurotic pupil. Patients with positive RAPD underwent a visual field examination with Humphrey automated perimetry that included visual field index (VFI), mean deviation (MD), and pattern standard deviation (PSD). Spearman’s rank correlation coefficients and linear regression were used to analyze the association between RAPD grades and visual field parameters. Results: RAPD clinical plus grades were correlated with interocular VFI (r = 0.55, P

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0267469

DOI: 10.1371/journal.pone.0267469

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