Survival and complications after neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy for esophageal squamous cell cancer: A meta-analysis

Yaru Guo, Mingna Xu, Yufei Lou, Yan Yuan, Yuling Wu, Longzhen Zhang, Yong Xin and Fengjuan Zhou

PLOS ONE, 2022, vol. 17, issue 8, 1-17

Abstract: Objectives: To compare the survival and complications of neoadjuvant chemoradiation (NCRT) versus neoadjuvant chemotherapy (NCT) for esophageal squamous cell carcinoma (ESCC). Methods: We conducted a systematic literature search of the PubMed, Web of Science, Cochrane Library, EMBASE, CNKI, Wanfang Data, CBM, and VIP databases from inception to November 2021. Meta-analyses were performed using RevMan (version 5.3) and Stata version 15.0. Results: A total of 18 studies were included, which involved 3137 patients, The results of the metaanalysis showed that the pathological complete remission rate (odds ratio [OR] = 5.21, 95% confidence interval [CI]: 2.85–9.50, p

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0271242

DOI: 10.1371/journal.pone.0271242

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