The causal relationship between allergic diseases and heart failure: Evidence from Mendelian randomization study

Yan-Ge Guo, Yan Zhang and Wei-Li Liu

PLOS ONE, 2022, vol. 17, issue 7, 1-12

Abstract: Background: Emerging evidence shows allergic diseases, such as atopic dermatitis and asthma, are risk factors of heart failure. However, the causal relationship between allergic diseases and heart failure is not clear. Methods: We performed a two-sample Mendelian randomization analysis between allergic diseases and heart failure using summary statistics of genome-wide association studies from large GWAS consortia, with total sample size of 1.2 million. Independent instrumental variables for asthma and atopic dermatitis (P

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0271985

DOI: 10.1371/journal.pone.0271985

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