Prognostic factors for favorable outcomes after veno-venous extracorporeal membrane oxygenation in critical care patients with COVID-19

Bärbel Kieninger, Magdalena Kilger, Maik Foltan, Michael Gruber, Dirk Lunz, Thomas Dienemann, Stephan Schmid, Bernhard Graf, Clemens Wiest, Matthias Lubnow, Thomas Müller, Bernd Salzberger, Wulf Schneider-Brachert and Martin Kieninger

PLOS ONE, 2023, vol. 18, issue 1, 1-15

Abstract: Background: Patients with COVID-19 and severe acute respiratory failure may require veno-venous extracorporeal membrane oxygenation (VV ECMO). Yet, this procedure is resource-intensive and high mortality rates have been reported. Thus, predictors for identifying patients who will benefit from VV ECMO would be helpful. Methods: This retrospective study included 129 patients with COVID-19 and severe acute respiratory failure, who had received VV ECMO at the University Medical Center Regensburg, Germany, between 1 March 2020 and 31 December 2021. Patient-specific factors and relevant intensive-care parameters at the time of the decision to start VV ECMO were investigated regarding their value as predictors of patient survival. In addition, the intensive-care course of the first 10 days of VV ECMO was compared between survivors and patients who had died in the intensive care unit. Results: The most important parameters for predicting outcome were patient age and platelet count, which differed significantly between survivors and non-survivors (age: 52.6±8.1 vs. 57.4±10.1 years, p

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0280502

DOI: 10.1371/journal.pone.0280502

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