Recruitment strategies and HPV self-collection return rates for under-screened women for cervical cancer prevention

Jennifer S Smith, Olivia M Vaz, Charley E Gaber, Andrea C Des Marais, Bhavika Chirumamilla, Lori Hendrickson, Lynn Barclay, Alice R Richman, Xian Brooks, Anna Pfaff and Noel T Brewer

PLOS ONE, 2023, vol. 18, issue 3, 1-11

Abstract: In the United States, medically underserved women carry a heavier burden of cancer incidence and mortality, yet are largely underrepresented in cancer prevention studies. My Body, My Test is a n observational cohort, multi-phase cervical cancer prevention study in North Carolina that recruited low-income women, aged 30–65 years and who had not undergone Pap testing in ≥ 4 years. Participants were offered home-based self-collection of cervico-vaginal samples for primary HPV testing. Here, we aimed to describe the recruitment strategies utilized by study staff, and the resulting recruitment and self-collection kit return rates for each specific recruitment strategy. Participants were recruited through different approaches: either direct (active, staff-effort intensive) or indirect (passive on the part of study staff). Of a total of 1,475 individuals screened for eligibility, 695 were eligible (47.1%) and 487 (70% of eligible) participants returned their self-collection kit. Small media recruitment resulted in the highest number of individuals found to be study eligible, with a relatively high self-collection kit return of 70%. In-clinic in-reach resulted in a lower number of study-eligible women, yet had the highest kit return rate (90%) among those sent kits. In contrast, 211 recruitment which resulted in the lowest kit return of 54%. Small media, word of mouth, and face-to-face outreach resulted in self-collection kit return rates ranging from 72 to 79%. The recruitment strategies undertaken by study staff support the continued study of reaching under-screened populations into cervical cancer prevention studies.

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0280638

DOI: 10.1371/journal.pone.0280638

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