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Imputation of missing values for cochlear implant candidate audiometric data and potential applications

Cole Pavelchek, Andrew P Michelson, Amit Walia, Amanda Ortmann, Jacques Herzog, Craig A Buchman and Matthew A Shew

PLOS ONE, 2023, vol. 18, issue 2, 1-20

Abstract: Objective: Assess the real-world performance of popular imputation algorithms on cochlear implant (CI) candidate audiometric data. Methods: 7,451 audiograms from patients undergoing CI candidacy evaluation were pooled from 32 institutions with complete case analysis yielding 1,304 audiograms. Imputation model performance was assessed with nested cross-validation on randomly generated sparse datasets with various amounts of missing data, distributions of sparsity, and dataset sizes. A threshold for safe imputation was defined as root mean square error (RMSE) 99%) of audiograms with RMSE well below a clinically significant threshold of 10dB. Evaluation across a range of dataset sizes and sparsity distributions suggests a high degree of generalizability to future applications.

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0281337

DOI: 10.1371/journal.pone.0281337

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