Health professionals’ perceptions on local production and bioequivalence study of generic medicines: A cross-sectional survey of physicians and pharmacy professionals in Addis Ababa, Ethiopia

Muluken Nigatu Selam, Abrham Temesgen Mengstu, Atalay Mulu Fentie, Gebremedhin Beedemariam Gebretekle, Eskinder Eshetu Ali and Anteneh Belete

PLOS ONE, 2023, vol. 18, issue 3, 1-14

Abstract: Local production of generic medicines in developing countries has a critical role to meet public health needs by ensuring the availability of essential medicines and providing patients’ relief from the burden of unaffordable medical bills. Compliance with bioequivalence (BE) requirements increase the quality and competitiveness of generic drugs regardless of the source. In this regard, a regional BE center has been established in Addis Ababa, Ethiopia to serve the needs of Ethiopia and neighbouring countries. The present study aimed to assess the knowledge and perceptions of health professionals working in Addis Ababa regarding local production and BE studies of generic medicines. A cross-sectional survey was employed and physician participants working at public hospitals and pharmacists from various practice settings were selected using convenient sampling technique. Data was collected using self-administered structured questionnaire. Descriptive statistics was used to summarize the data and multinomial logistic regression analyses was used to assess predictors of health professionals’ perception towards the source of drugs. Statistically significant association was declared at p-value

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0281665

DOI: 10.1371/journal.pone.0281665

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