The ROX index (Index combining the respiratory rate with oxygenation) is a prognostic factor for acute respiratory distress syndrome

Kenta Nishiyama, Kazuya Ichikado, Keisuke Anan, Kazunori Nakamura, Kodai Kawamura, Moritaka Suga and Takuro Sakagami

PLOS ONE, 2023, vol. 18, issue 2, 1-11

Abstract: Background: There is no existing reliable and practical method for predicting the prognosis of acute respiratory distress syndrome (ARDS). Objective: We aimed to clarify the association between the ROX index, which is calculated as the ratio of peripheral oxygen saturation divided by the fraction of inspired oxygen to the respiratory rate, and the prognosis of patients with ARDS under ventilator support. Methods: In this single-center retrospective cohort study from prospectively collected database, eligible patients were categorized into three groups based on ROX tertiles. The primary outcome was the 28-day survival, and the secondary outcome was 28-day liberation from ventilator support. We performed multivariable analysis using the Cox proportional hazards model. Results: Among 93 eligible patients, 24 (26%) patients died. The patients were divided into three groups according to the ROX index (

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0282241

DOI: 10.1371/journal.pone.0282241

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