Sex-based differences in long-term outcomes after stroke: A meta-analysis

Xiumei Guo, Yu Xiong, Xinyue Huang, Zhigang Pan, Xiaodong Kang, Chunhui Chen, Jianfeng Zhou, Hanlin Zheng, Yuping Chen, Weipeng Hu, Lingxing Wang and Feng Zheng

PLOS ONE, 2023, vol. 18, issue 4, 1-13

Abstract: Background: There is limited data on sex-related disparities in the long-term outcomes after stroke. We aim to investigate whether there are sex-based differences in long-term outcomes using pooled data. Methods: Three databases (PubMed, Embase, and Cochrane Library) were systematically searched from inception to July 2022. This meta-analysis was performed in accordance with the recommendations and guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The modified Newcastle-Ottawa scale was used to assess the risk of bias. In addition, a random-effects model was used. Results: Twenty-two cohort studies with 84538 patients were included. There were 50.2% men and 49.8% women. Women had a higher mortality at 1 (odds ration [OR], 0.82; 95% confidence interval [CI][0.69, 0.99], P = 0.03) and 10 (OR 0.72, 95% CI[0.65, 0.79], P

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0283204

DOI: 10.1371/journal.pone.0283204

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