Evaluation of 25-hydroxyvitamin D (25(OH)D) levels before and during the COVID-19 pandemic: A cross-sectional study and trend analysis involving 86,772 samples

Mehmet Emin Arayıcı, Sila Ovgu Korkut-Uysal, Asim Leblebici, Zeynep Akcali, Deniz Tuna Edizer, Seher Kabul, Dilek Cimrin and Ender Berat Ellidokuz

PLOS ONE, 2023, vol. 18, issue 5, 1-13

Abstract: Background: The aim of this paper was to evaluate the change in 25-hidroxyvitamin D (25(OH)D) levels before and during the COVID-19 pandemic. Methods: In this retrospective, cross-sectional and methodological study included 86,772 patients (18–75 years) samples who were admitted to the Izmir Dokuz Eylul University Hospital (latitude and longitude (Turkey): 27 E 09; 38 N 25, respectively) for various reasons and whose 25(OH)D levels were measured in the biochemistry unit between 2019–2020 and 2020–2021 (before and during the COVID-19 outbreak). A time series analysis of monthly averages for 25(OH)D was performed. For the purpose of seasonal study, the mean levels of 25(OH)D are grouped by years. Data were modeled in terms of 25(OH)D levels using the MATLAB Curve Fitting Toolbox. Results: There was no significant difference between the sexes according to 25(OH)D levels (p>0.05). 25(OH)D levels were significantly higher in the summer months and lower in the winter months (p

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0284647

DOI: 10.1371/journal.pone.0284647

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