Early versus late amniotomy during induction of labor using oxytocin: A randomized controlled trial

Ahmed Halouani, Yassine Masmoudi, Rym Hamdaoui, Aymen Hammami, Amel Triki and Anissa Ben Amor

PLOS ONE, 2023, vol. 18, issue 5, 1-11

Abstract: Objective: To assess the effect of early amniotomy on labor duration, maternal and neonatal outcomes during induction of labor (IOL). Methods: This was a randomized controlled trial, conducted over a period of eight months at a monocentric site. Singleton pregnancies in nulliparous and parous patients with cephalic presentation and Bishop score ≥ 6 were enrolled in the study. One hundred participants were randomized into two groups: early amniotomy (initiating IOL with amniotomy followed by oxytocin) versus late amniotomy (initiating IOL with oxytocin followed by amniotomy 4 hours later). The primary endpoint was the time to active phase (cervical dilation ≥ 5 cm) during IOL. Secondary outcomes were time to vaginal delivery, mode of delivery, and maternal and fetal outcomes. Results: Early amniotomy reduced time to active phase by 2 hours and 46 minutes compared to the late amniotomy group (3 h 42 min vs. 6 h 28 min; p

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0286037

DOI: 10.1371/journal.pone.0286037

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