Low skeletal muscle mass index and all-cause mortality risk in adults: A systematic review and meta-analysis of prospective cohort studies

Yahai Wang, Donglin Luo, Jiahao Liu, Yu Song, Binggang Jiang and Haichao Jiang

PLOS ONE, 2023, vol. 18, issue 6, 1-17

Abstract: Objective: The relationship between low skeletal muscle mass index (SMI) and all-cause mortality risk in the general adults remains unclear. Our study was conducted to examine and quantify the associations between low SMI and all-cause mortality risks. Methods: PubMed, Web of Science, and Cochrane Library for primary data sources and references to relevant publications retrieved until 1 April 2023. A random-effect model, subgroup analyses, meta-regression, sensitivity analysis, and publication bias were conducted using STATA 16.0. Results: Sixteen prospective studies were included in the meta-analysis of low SMI and the risk of all-cause mortality. A total of 11696 deaths were ascertained among 81358 participants during the 3 to 14.4 years follow-up. The pooled RR of all-cause mortality risk was 1.57 (95% CI, 1.25 to 1.96, P

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0286745

DOI: 10.1371/journal.pone.0286745

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