Constructing of predictive model for the surgical effect of patients with cleft lip and palate

Na Liu, Jingyuan Yang, Fang Tan and Haijian Zhu

PLOS ONE, 2023, vol. 18, issue 6, 1-16

Abstract: Objective: To explore effective factors of surgical effect for patients with cleft lip and palate, and to construct the predictive model of surgical effect, which provide reference for improving the effect of cleft lip and palate surgery. Methods: This study has been ethically reviewed and approved by the Medical Ethics Committee of Guiyang Stomatological Hospital before the study began.A total of 997 cases of cleft lip and palate surgical treatment in Guiyang Stomatological Hospital from 2015 to 2020 were collected. Logistic regression analysis was used to analyze the factors influencing the surgical outcome, and a score system was established by assigning values to the influencing factors using the nomogram. Data of 110 patients were verified, and decision curve analysis was used to evaluate the predicted results. Results: Logistic regression analysis showed that the number of surgeries, surgical methods, breast milk, prenatal examination, nutrition during pregnancy and labor intensity during pregnancy were independent risk factors for poor surgical results (all P

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0286976

DOI: 10.1371/journal.pone.0286976

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