Effect of external therapies of traditional Chinese medicine on constipation in patients with CRF: A meta-analysis

Yu Wu, Qisu Ying, Yajing He, Xiangcheng Xie, Xiao Yuan, Ming Wang, Xiao Fei and Xiu Yang

PLOS ONE, 2023, vol. 18, issue 10, 1-14

Abstract: Objective: The purpose of this study was to evaluate the curative effect of external therapies of traditional Chinese medicine on constipation in patients with chronic renal failure and to provide scientific theoretical basis for clinical practice. Method: We searched the English database of PubMed, EMBASE, the Cochrane Library and the Web of Science and Chinese database of CNKI, Wan fang database, VIP Database and China Biomedical Literature Database up to December 2022. Randomized controlled trials (RCTs) involving constipation in patients with CRF that compared external therapies of traditional Chinese medicine and routine treatment to routine treatment were eligible for the analysis. A meta-analysis of the outcome indicators including total efficiency, weekly defecation times, defecation time, defecation difficulty score, patient-assessment of constipation quality of life and adverse events of treatment were performed. The analysis was performed by using Review Manager version 5.3. Result: A total of 23 studies were included, with 1764 patients. Meta-analysis results showed that compared with the control group, the test group could significantly increase weekly defecation times(MD = 0.94, 95%CI(0.70, 1.18), Z = 7.74, P

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0291968

DOI: 10.1371/journal.pone.0291968

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