Notes on correctness of p-values when analyzing experiments using SAS and R

Razaw Al-Sarraj and Johannes Forkman

PLOS ONE, 2023, vol. 18, issue 11, 1-17

Abstract: It is commonly believed that if a two-way analysis of variance (ANOVA) is carried out in R, then reported p-values are correct. This article shows that this is not always the case. Results can vary from non-significant to highly significant, depending on the choice of options. The user must know exactly which options result in correct p-values, and which options do not. Furthermore, it is commonly supposed that analyses in SAS and R of simple balanced experiments using mixed-effects models result in correct p-values. However, the simulation study of the current article indicates that frequency of Type I error deviates from the nominal value. The objective of this article is to compare SAS and R with respect to correctness of results when analyzing small experiments. It is concluded that modern functions and procedures for analysis of mixed-effects models are sometimes not as reliable as traditional ANOVA based on simple computations of sums of squares.

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0295066

DOI: 10.1371/journal.pone.0295066

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