Prevalence and risk factors of early postoperative seizures in patients with glioma: A protocol for meta-analysis and systematic review

Bo Sun, Wenpeng Lu, Wangyang Yu, Ye Tian and Peng Wang

PLOS ONE, 2024, vol. 19, issue 4, 1-8

Abstract: Introduction: Early postoperative seizures has been the most common clinical expression in gliomas; however, the incidence and risk factors for early postoperative seizures in gliomas are more controversial. This protocol describes a systematic review and meta-analysis to clarify the prevalence and risk factors of early postoperative seizures in patients with glioma. Methods and analysis: Searches will be conducted on CNKI, WanFang, VIP, PubMed, Embase, Cochrane Library databases and Web of Science for the period from database inception to December 31st, 2023. Case-control and cohort studies of the incidence and risk factors for early postoperative seizures in all gliomas will be included. The primary outcome will be incidence, risk factors. Newcastle-Ottawa Scale was used for quality evaluation. Review of article screening, extracting data and risk of bias assessment will be repeated by two independent reviewers. Result: This study will provide evidence for the risk factors and incidence of early postoperative seizures in patients with glioma. Conclusion: Our study will provide evidence for the prevention of early postoperative seizures in glioma patients. Trail registration: This protocol was registered in PROSPERO and registration number is CRD42023415658.

Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0301443

DOI: 10.1371/journal.pone.0301443

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