Predictive role of preoperative sarcopenia for long-term survival in rectal cancer patients: A meta-analysis

Qiutong Su and Jia Shen

PLOS ONE, 2024, vol. 19, issue 5, 1-13

Abstract: Purpose: To identify the predictive role of sarcopenia in long-term survival among rectal cancer patients who underwent surgery based on available evidence. Methods: The Medline, EMBASE and Web of Science databases were searched up to October 20, 2023, for relevant studies. Overall survival (OS), disease-free survival (DFS) and cancer-specific survival (CSS) were the endpoints. Hazard ratios (HRs) and 95% confidence intervals (CIs) were combined to evaluate the association between sarcopenia and survival. Results: Fifteen studies with 4283 patients were included. The pooled results demonstrated that preoperative sarcopenia significantly predicted poorer OS (HR = 2.07, 95% CI = 1.67–2.57, P

Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0303494

DOI: 10.1371/journal.pone.0303494

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