Effects of intraocular pressure change on intraocular lens power calculation in primary open-angle glaucoma and ocular hypertension

Chareenun Chirapapaisan, Akarawit Eiamsamarng, Niphon Chirapapaisan, Wara Raksong, Darin Sakiyalak, Sunisa Koodkaew and Audcharawadee Subunnasenee

PLOS ONE, 2024, vol. 19, issue 6, 1-8

Abstract: This study aimed to assess the effect of intraocular pressure (IOP) changes on biometry and intraocular lens (IOL) power calculation in patients diagnosed with primary open-angle glaucoma (POAG) and ocular hypertension (OHT). This prospective non-randomized cohort study enrolled patients with diagnosed POAG and OHT, presenting with IOP levels exceeding 25 mmHg. Thai Clinical Trials Registry number was TCTR20180912007. Optical biometry, encompassing measurements such as corneal thickness (CCT), keratometry, anterior chamber depth (ACD), and axial length, was conducted before and after IOP reduction. The IOL power was also determined using the SRK/T formula. The main outcomes measured were alterations in biometry and IOL power. Correlations between IOP, biometric parameters, and IOL power were analyzed. In total, 28 eyes were included in the study, with a mean patient age of 65.71±10.2 years. After IOP reduction, all biometric parameters, except CCT and ACD, exhibited a decrease without reaching statistical significance (all p>0.05). Meanwhile, IOL power showed a slight increase of 0.214±0.42 diopters (P = 0.035). The correlation between IOP and biometric parameters was found to be weak. However, there was a moderate correlation between IOP and IOL power (r2 = 0.267). Notably, IOL power tended to increase by more than 0.5 diopters when IOP decreased by more than 10 mmHg (p

Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0304169

DOI: 10.1371/journal.pone.0304169

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