Central venous pressure as a method of optimising atrio-ventricular delay after cardiac surgery

Alexander Tindale, Ioana Cretu, Naomi Gomez, Ross Haynes, Hongying Meng, Mark J Mason and Darrel P Francis

PLOS ONE, 2025, vol. 20, issue 1, 1-13

Abstract: Introduction: Haemodynamic atrioventricular delay (AVD) optimisation has primarily focussed on signals that are not easy to acquire from a pacing system itself, such as invasive left ventricular catheterisation or arterial blood pressure (ABP). In this study, standard clinical central venous pressure (CVP) signals are tested as a potential alternative. Methods: Sixteen patients with a temporary pacemaker after cardiac surgery were studied. AV delay optimisation was performed by alternating between a reference AVD of 120ms and tested settings ranging from 40 to 280ms, with 8 replicates for each setting. Alongside (a) the raw data, three methods of correcting for respiration were tested: (b) limiting analysis to a respiratory cycle, (c) asymmetric least squares (ALS) and (d) discrete wavelet transform (DWT). The utility of a quality control step was tested. Results: CVP signals were a mirror image of the systolic ABP signals: The four R values were -0.674, -0.692, -0.631, -0.671 respectively (all p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0310905

DOI: 10.1371/journal.pone.0310905

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