The association between subfoveal choroidal thickness and refractive error in Taiwanese children: A cross-sectional study

Li-Ying Huang, Lu-Ting Yu, Ning-Yi Hsia, Yi-Ching Hsieh and Hui-Ju Lin

PLOS ONE, 2025, vol. 20, issue 5, 1-9

Abstract: Purpose: The aim was to analyze the association of subfoveal choroidal thickness (SFCT) with age, best-corrected visual acuity, refractive error, and axial length in Taiwan pediatric population. Methods: A total of 374 eyes in 187 children were enrolled in this retrospective cross-sectional comparative study, who underwent examinations of best-corrected visual acuity (BCVA), cycloplegic refraction, and axial length (AL). Subfoveal choroidal thickness was assessed utilizing spectral domain enhanced depth imaging optical coherence tomography (EDI-OCT), with measurements taken at the subfovea, defined as the distance from the retinal pigment epithelium to the chorioscleral border. Results: The mean age was 5.6 ± 1.9 years (range 2–16 years). The cycloplegic spherical equivalent refractive error was between + 7.25 and - 15.25 diopters (D) and cycloplegic sphere power was between + 8.25 and - 11.5 diopters (D). The mean SFCT was 299.0 ± 69.80 μm. The mean axial length was 22.87 ± 1.29 mm. In univariate analysis, SFCT had significant positive correlations with spherical equivalent (SE) and sphere power (p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0316306

DOI: 10.1371/journal.pone.0316306

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