Neonatal outcomes and resuscitation practices following the addition of heart rate-guidance to basic resuscitation

Jackie K Patterson, Daniel Ishoso, Adrien Lokangaka, Pooja Iyer, Casey Lowman, Joar Eilevstjønn, Ingunn Haug, Beena D Kamath-Rayne, Eric Mafuta, Helge Myklebust, Tracy Nolen, Antoinette Tshefu, Carl Bose and Sara Berkelhamer

PLOS ONE, 2025, vol. 20, issue 1, 1-13

Abstract: Aim: To evaluate the impact of heart rate-guided basic resuscitation compared to Helping Babies Breathe on neonatal outcomes and resuscitation practices in the Democratic Republic of the Congo. Methods: We conducted a pre-post clinical trial comparing heart rate-guided basic resuscitation to Helping Babies Breathe in three facilities, enrolling in-born neonates ≥28 weeks gestation. We collected observational data during a convenience sample of resuscitations and extracted clinical data from the medical record for all participants. We evaluated our primary outcome of effective breathing at three minutes after birth among newborns not breathing well at 30 seconds after birth employing generalized linear models using maximum likelihood estimation. Results: Among 1,284 newborns with observational data, there was no difference in the proportion effectively breathing at three minutes (adjusted relative risk 1.08 [95% CI 0.81, 1.45]). Among 145 receiving bag mask ventilation, time to bag mask ventilation decreased 64.3 seconds during heart rate-guided resuscitation (p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0317199

DOI: 10.1371/journal.pone.0317199

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