The Lived Fracture Experience (LiFE) study: A mixed methods qualitative study research protocol exploring the lived experiences of fracture non-union patients

Irene Yang, Carol Porteous and Hamish Simpson

PLOS ONE, 2025, vol. 20, issue 4, 1-10

Abstract: Background: Fractures are a common and a major cause of disability and death, with up to 10% of fractures failing to heal normally. These fractures are called “fracture non-unions”. Currently, debate on the impact of non-union in the medical and research communities exists. Unfortunately, this indirectly minimizes the impact of fracture non-unions, and hinders further research work which could reduce unnecessary patient suffering. In this study, we aim to explore the lived experiences of fracture non-union patients in one-on-one interviews to determine whether fracture non-union is a burden for patients, and if so, to outline the burden on patients and their close circles. Methods: Eligible participants will include adult patients who currently have/previously (in the last 36 months) had a long bone fracture that has not healed normally. Data will be collected through in-depth face-to-face or telephone interviews, complemented by quantitative data captured using the standardized Euroqol EQ-5D-5L questionnaire. With consent, interviews will be audio-recorded and transcribed verbatim. Using NVIVO software, we will develop grouped codes and categories to describe and provide insight into the experience of fracture non-union patients. EQ-5D-5L, and EQ VAS data will be presented using a measure of central tendency and a measure of dispersion to provide insight into the overall health related quality of life for patients. Ethics and dissemination: The study was approved by the Health Research Authority and Health and Care Research Wales Approval (approval date: 27 March 2024; IRAS project ID: 337652). Results from this study aim to improve the information and support provided to fracture non-union patients. Findings will be disseminated to the study participants, healthcare professionals, and local commissioners through peer-reviewed articles and at academic conferences.

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0318636

DOI: 10.1371/journal.pone.0318636

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