Association between red blood cell distribution width-to-albumin ratio at admission and all-cause mortality in patients with acute pancreatitis based on the MIMIC-III database

Qingsong Wu, Lianyi Liao and Qingjun Deng

PLOS ONE, 2025, vol. 20, issue 2, 1-16

Abstract: Objective: The association between red blood cell distribution width-to-albumin (RDW/ALB) ratio (RAR) and all-cause mortality in patients with acute pancreatitis has not been fully delineated. The purpose of this study was to investigate the impact of RAR at admission on 28-day all-cause mortality in patients with acute pancreatitis. Design: This investigation was conducted as a retrospective analysis utilizing data from the Medical Information Mart for Intensive Care (MIMIC)-III database. Participants: Patients with acute pancreatitis were selected from the MIMIC-III database according to predefined eligibility criteria. Outcome: The outcome was the all-cause mortality rates within 28 days. Results: Upon screening and excluding ineligible participants, a total of 931 patients with acute pancreatitis who met the inclusion criteria were analyzed. The overall mortality at 28 days was 11.71%. The receiver operating characteristic (ROC) analysis indicated that RAR had a moderate predictive value for all-cause mortality at 28 days, with an area under the curve (AUC) of 0.669 (95%CI, 0.617–0.720; p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0318873

DOI: 10.1371/journal.pone.0318873

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