Association between arsenic exposure and intrauterine growth restriction: A systematic review and meta-analysis

Jing Jiang, Xuan Zuo, Songlin An, Jing Yang, Linfei Wu, Rong Zeng, Qiongdan Hu, Lu Fan, Haiyu Wang, Chuanwu Yang, Yihan Liang, Yuanzhong Zhou, Hong Pan and Yan Xie

PLOS ONE, 2025, vol. 20, issue 6, 1-18

Abstract: Several observational studies have explored the link between arsenic (As) exposure and intrauterine growth restriction (IUGR). However, epidemiological findings have been inconsistent, with a wide range of reported heterogeneity. This study aims to systematically evaluate the association between As exposure and IUGR (SGA(Small for gestational age), PTB(Preterm birth), LBW(Preterm birth)) through a meta-analysis. We searched six databases—China National Knowledge Infrastructure, Wan Fang, VIP Database, PubMed, Web of Science, and Science Direct—for studies on As exposure and IUGR up to May 2024. After screening and data extraction, a comprehensive bias risk assessment was conducted using the Newcastle-Ottawa Scale (NOS), AHRQ (the assessment tool of the Agency for Healthcare Research and Quality), and NTP/OHAT (the assessment tool of the National Toxicology Program/Office of Health Assessment and Translation). Meta-analysis was conducted using random-effects models (I2 > 50%) or fixed-effects models (I2

Date: 2025
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0320603 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 20603&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0320603

DOI: 10.1371/journal.pone.0320603

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().